In the field of life sciences, where innovation is not only a key to success but also a necessity, new challenges frequently arise. Companies often lack not only technical or scientific solutions but also the interdisciplinary collaboration that is essential for developing biotechnology, medical devices, and other complex projects. Biohackathons, such as “Biospark – Hack the Future of Biotech,” are among the initiatives addressing these challenges. This event, held on December 2–4 at the newly opened Vilnius University Medical Sciences Center, united life sciences students, researchers, and business representatives. It was organized by The COINS 2025 and BSV Ventures, with support from the National Cancer Institute (NCI), which presented one of the event’s challenges.