Scientists at the Vilnius University Life Sciences Center (VU LSC) investigate the structures of biological molecules, their interactions, and develop methods to assess the reliability of computationally predicted structures.
In recent years, artificial intelligence–based tools have fundamentally transformed the ability to predict protein structures. The most prominent example is the AlphaFold model, whose developers were awarded the Nobel Prize in Chemistry in 2024. Nevertheless, even the most advanced methods do not always enable accurate prediction of all biomolecular structures, leaving scientists still to evaluate computational models reliably.