Surgical treatment still remains the only and main treatment method that allows you to expect a complete recovery from tumours of the digestive tract. Despite the advanced operations in medicine, surgery for tumours of the digestive tract remains extremely difficult and is associated with a high rate of postoperative complications, which can reach 40-60%. The most common postoperative complications are various postoperative infections. Early diagnosis of postoperative infections is extremely important, as this allows early treatment to prevent adverse complications. Currently, clinicians use long-established and widely used biomarkers, such as C-reactive protein, white blood cell count, or procalcitonin concentration, for early diagnosis of infectious complications. However, current biomarkers are not accurate enough to diagnose infection early enough, resulting in a 2-5% mortality rate after surgery for gastrointestinal cancer. In order to reduce deaths from infectious complications, it is necessary to discover new diagnostic and/or predictive biomarkers, which should be non-invasive or minimally invasive, and reliably determined in body fluids of patients by molecular methods. This study would be an interdisciplinary work of biological and medical sciences, with the aim of conducting comprehensive biomarker studies and identifying innovative biomarkers for the diagnosis and/or prediction of postoperative infections among patients with digestive tract cancer.
Mokslinis vadovas / supervisor: Dr. Rasa Sabaliauskaitė
Kontaktai / contacts:
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tel. / phone: (8 5) 219 0924