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Electrochemical biosensors are widely used to detect various analytes, from glucose to protein-based antibodies that adsorb to the electroactive surface. Many medical diagnostic procedures that require fast and accurate analysis rely on such technologies. Despite the overwhelming number of different biosensors that have been reported, most are based on electrochemical detection on a single sensor surface using classical potential switching techniques or current detection at a fixed electrode potential. The aim of this PhD thesis is to apply orchestrated (synchronized) fast cycling electrochemical techniques for the analysis of enzymatic reactions and/or the adsorption of biomolecules on multiple electrodes in singular biosensor systems. The expected novelties: i) enabling new bioelectrochemical designs for the detection of unresearched analytes; ii) improving the signal-to-noise ratio in the extraction of useful signals from complex interfering media such as blood; iii) improving the throughput of analyses with multiple test points. Following successful development of the technologies, the PhD student would be offered the opportunity to participate in the commercialization of the technologies.

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