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Our ORCID 0000-0002-3997-2355

2021

Jarazo J., Barmpa K., Modamio J., Saraiva C., Sabaté S, Rosety I., Griesbeck A., Skwirblies F., Zaffaroni G., Smits L., Su J., Arias J., Walter J., Gomez G., Monzel A., Qing X., Vitali A., Cruciani G, Boussaad I., Brunelli F., Jäger C., Rakovic A., Li W., Yuan L., Berger E., Arena G. , Bolognin S., Schmidt R., Schröder C., Antony P., Klein C., Krüger R., Seibler P., Schwamborn J. (2021). "Parkinson's Disease Phenotypes in Patient Neuronal Cultures and Brain Organoids Improved by 2-Hydroxypropyl-β-Cyclodextrin Treatment"
Mov Disord. doi:10.1002/mds.28810. article

Arias J., Yu J., Varshney M., Inzunza J., Nalvarte I. (2021). "HSC and iPS cell‐derived CAR‐NK cells as reliable cell‐based therapy solutions". Stem cell Tra Med. doi:10.1002/sctm.20-0459. article

2020

Inzunza J., Arias J., Segura-Aguilar J., Nalvarte I., Varshney M. (2020). "Generation of nonviral integration-free human iPS cell line KISCOi001-A from normal human fibroblasts, under defined xeno-free and feeder-free conditions." Stem Cell Res. doi:10.1016/j.scr.2021.102193. article

Barbuti P., Antony P., Santos B., Massart F., Cruciani G., Dording C., Arias J., Schwamborn J., Krüger R. (2020). "Using High-Content Screening to Generate Single-Cell Gene-Corrected Patient-Derived iPS Clones Reveals Excess alpha-synuclein with Familial Parkinson’s Disease Point Mutation A30P". Cells. doi:10.3390/cells9092065 article

2019

Gomez-Giro, G., Arias J., Schöler, Hans, et al. (2019). "Synapse alterations precede neuronal damage and storage pathology in a human cerebral organoid model of CLN3-juvenile neuronal ceroid lipofuscinosis." Acta Neuropathol Commun. doi:10.1186/s40478-019-0871-7. article

Arias J. et al. (2019). "Generation of human induced pluripotent stem cell lines from patients with selective IgA deficiency." Stem Cell Res. doi:10.1016/j.scr.2019.101613. article

Arias J. et al. (2019). "Generation of a human induced pluripotent stem cell line (PHAi003) from a primary immunodeficient patient with CD70 mutation." Stem Cell Res. doi:10.1016/j.scr.2019.101612. article

Nie M., Du L., Zhang B., Ren W., Joung J., Ye X., Arias J., Shi X., Liu D., Wu K., Zhang F., et al. Essentiality of CREBBP in EP300 truncated B-cell lymphoma revealed by genome-wide CRISPR Cas9 screen. Biorxiv. (2019). doi:10.1101/746594 article

2018

Arias J. et al., (2018.) "Automated high-throughput high-content autophagy and mitophagy phenotyping in Parkinson's disease." Sci Rep doi:10.1101/412957. article

Walter, J., Arias, J. et al. (2018). "Neural stem cells of Parkinson's Disease patients exhibit aberrant mitochondrial morphology and functionality." Stem Cell Reports. doi:10.1016/j.stemcr.2019.03.004. article

2017

Arias J., Schöler, Hans, et al., (2017). "FACS-assisted CRISPR Cas9 genome editing facilitates Parkinson's disease modeling." Stem Cell Reports. doi:10.1016/j.stemcr.2017.08.026. article

Qing X., Arias J., et al. (2017). "CRISPR/Cas9 and piggyBac-mediated footprint-free LRRK2- G2019S knock-in reveals neuronal complexity phenotypes and alpha-synuclein modulation in dopaminergic neurons." Stem Cell Res. doi:10.1016/j.scr.2017.08.013. article

Group of Targeted Delivery of CRISPR-Cas System and Cell/Immunotherapies

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